New spirocondensed quinazolinones and their use as...

C - Chemistry – Metallurgy – 07 – D

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C07D 239/80 (2006.01) A61K 31/517 (2006.01)

Patent

CA 2499330

The invention relates to compounds of formula (I): (see formula I) wherein R1, R2 and m are defined in the description, their use as medicament, pharmaceutical compositions containing them and a process for their preparation. These compounds act as phosphodiesterase inhibitors and inhibit in particular PDE-VII.

L'invention concerne des composés représentés par la formule (I): dans laquelle R<1>, R<2> et m sont définis dans le descriptif, leur utilisation en tant que médicament, des compositions pharmaceutiques les contenant et un procédé de préparation correspondant. Ces composés agissent en tant qu'inhibiteurs de phosphodiesterase et inhibent notamment PDE-VII.

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