Nicotinic acetylcholine receptor ligands 101

C - Chemistry – Metallurgy – 07 – D

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C07D 491/22 (2006.01) A61K 31/439 (2006.01) A61P 25/00 (2006.01) A61P 25/18 (2006.01) A61P 25/22 (2006.01) A61P 25/34 (2006.01)

Patent

CA 2652610

Nicotinic acetylcholine receptor ligands of Formula I, I wherein X, n, R1 and R2 are as described in the specification, diastereoisomers, enantiomers, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing, and methods for using the same.

La présente invention concerne les ligands du récepteur d'acétylcholine nicotinique de formule I, I dans laquelle X, n, R1 et R2 sont décrits dans la description comme étant des diastéréoisomères, des énantiomères, des sels pharmaceutiquement acceptables. L'invention concerne les procédés de fabrication, les compositions pharmaceutiques et les procédés d'utilisation.

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