Nk1 antagonists

Details Nk1 antagonists Nk1 antagonists

C - Chemistry, Metallurgy

07

D

C07D 207/273 (2006.01) A61K 31/4025 (2006.01) A61K 31/44 (2006.01) A61P 25/28 (2006.01) C07D 207/26 (2006.01) C07D 207/38 (2006.01) C07D 211/76 (2006.01) C07D 401/04 (2006.01)

Patent

CA 2466465

A NK1 antagonist having the formula (I), with the variables defined herein, which is useful for treating a number of disorders, including emesis, depression, anxiety and cough;. wherein the variables are as defined in the specification. A representative compound of the invention is: Formula (II).

L'invention concerne un agoniste de NK1 de la formule (I), dont les variables sont tels que définies dans le mémorandum descriptif, qui peut traiter un grand nombre de troubles, tels que le vomissement, la dépression, l'anxiété ou la toux. Un composé représentatif de l'invention est un composé de la formule (II).

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