Novel aminooligosaccharide derivative and process for...

Details Novel aminooligosaccharide derivative and process for... Novel aminooligosaccharide derivative and process for...

C - Chemistry, Metallurgy

12

P

C12P 19/28 (2006.01) C07H 15/26 (2006.01) C12N 9/99 (2006.01) A61K 31/71 (1995.01)

Patent

CA 2208707

The present invention relates to novel aminooligosaccharide derivative and pharmaceutically acceptable non-toxic salts thereof, which possess potent saccharide hydrolase inhibition and antibacterial activities. The invention also relates to a process for preparing the same and to pharmaceutical compositions containing the same as active ingredients. In accordance with the present invention, the inventors isolated novel aminooligosaccharide derivative from a soil microorganism categorized as Streptomyces sp., and discovered that it can be applied as potent inhibitors for saccharide hydrolases and antibacterial agents as well.

L'invention porte sur un nouveau dérivé amino-oligoside et sur ses sels atoxiques acceptables sur le plan pharmaceutique, qui sont de puissants inhibiteurs d'hydrolases de saccharide et exercent une activité antibactérienne. L'invention porte également sur un procédé destiné à leur préparation et sur des compositions pharmaceutiques à base de ces principes actifs. D'après cette invention, les inventeurs ont isolé un nouveau dérivé amino-oligoside à partir d'un micro-organisme du sol appartenant à l'espèce Streptomyces, et ont découvert qu'il pouvait être administré comme un puissant inhibiteur des hydrolases de saccharide et comme bactéricide.

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