Novel antibodies that bind to antigenic polypeptides,...

C - Chemistry – Metallurgy – 12 – N

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Details

C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61P 35/00 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 15/63 (2006.01) C12P 21/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2446437

Disclosed herein are nucleic acid sequences that encode polypeptides. Also disclosed are antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids, polypeptides, or antibodies, or fragments thereof.

Cette invention concerne des séquences d'acides nucléiques qui codent des polypeptides. L'invention concerne également des anticorps qui se lient de manière immunospécifique au polypeptide, ainsi que des dérivés, des variants, des mutants ou des fragments desdits polypeptide, polynucléotide et anticorps. L'invention concerne en outre des procédés thérapeutiques, diagnostiques et de recherche servant au diagnostic, au traitement et à la prévention de troubles dans lesquels interviennent un des nouveaux acides nucléiques, polypeptides ou anticorps humains, ou des fragments de ceux-ci.

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