Novel antibody construct

Details Novel antibody construct Novel antibody construct

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) C07K 16/00 (2006.01) C07K 16/30 (2006.01) C07K 16/46 (2006.01) C12N 1/21 (2006.01) C12N 15/13 (2006.01)

Patent

CA 2126967

2126967 9409817 PCTABS00032 An antigen binding protein construct or "minibody" which includes the VL and VH domains of a native antibody fused to the hinge region and CH3 domain of the immunoglobulin molecule is described. Minibodies are small versions of whole antibodies which encode in a single chain the essential elements of a whole antibody. Minibodies are expressed by host cells transformed with minibody genes.

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