Novel benzopyran or thiobenzopyran derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 311/84 (2006.01) A61K 31/35 (2006.01) C07D 311/58 (2006.01) C07D 335/06 (2006.01) C07D 405/04 (2006.01) C07D 405/06 (2006.01) C07D 407/04 (2006.01) C07D 407/06 (2006.01) C07D 409/04 (2006.01) C07D 413/04 (2006.01) C07D 413/06 (2006.01) C07D 417/06 (2006.01)

Patent

CA 2334634

The present invention relates to a novel benzopyran or thiobenzopyran derivative represented by formula (1): pharmaceutically acceptable salt or stereoisomer thereof, in which X, R1, R2, R3, R4 and A are defined as described in the specification, and to a process for preparation thereof and a pharmaceutical composition having anti-estrogenic activity which contains the compound (1) as an active component.

L'invention concerne un nouveau dérivé de benzopyran ou de thiobenzopyran représenté par la formule (1), ou bien un sel pharmaceutiquement acceptable ou un stéréoisomère de ce dérivé. Dans ladite formule, X, R¿1?, R¿2?, R¿3?, R¿4? et A sont tels que définis aux fins de l'invention. L'invention concerne également un procédé relatif à l'élaboration de ce type de produit et une composition pharmaceutique à activité anti-oestrogénique renfermant le composé de formule (1) considéré, comme principe actif.

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