Novel compounds of reverse-turn mimetics, method for...

Details Novel compounds of reverse-turn mimetics, method for... Novel compounds of reverse-turn mimetics, method for...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) C07D 403/02 (2006.01)

Patent

CA 2758904

Disclosed are novel reverse turn mimetics based on the framework of pyrazino-triazinone, and the use thereof in the treatment of cancers, particularly, acute myeloid leukemia. A method is also provided for manufacturing the reverse turn mimetics on a mass scale.

Cette invention concerne de nouveaux mimétiques à spire inversée basés sur la structure de la pyrazino-triazinone, et leur utilisation pour traiter les cancers, en particulier, la leucémie myéloïde aiguë. Un procédé est également décrit pour préparer lesdits mimétiques à spire inversée à l'échelle industrielle.

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