C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/08 (2006.01) A61K 31/439 (2006.01) A61K 31/675 (2006.01) A61P 31/04 (2006.01)
Patent
CA 2716914
The present invention relates to novel crystalline forms of sodium salt of trans-7- oxo-6-(sulphooxy)-1,6-diazabicyclo[3,2,1]octane-2-carboxamide (e.g., NXL-104) thereof. The present invention relates to compositions comprising a crystalline form of sodium salt of trans-7-oxo-6-(sulphooxy)-1,6-diazabicyclo[3,2,1]octane-2- carboxamide (e.g., NXL-104) alone or in combination with an antibacterial agent (e.g., ceftaroline fosamil). Processes for the preparation of the crystalline forms and methods of treating bacterial infections by administering the crystalline forms alone or in combination with an antibacterial agent (e.g., ceftaroline fosamil) are also described.
Bhattacharya Sisir
Bonnet Alain
Dedhiya Mahendra G.
Ducandas Veronique
Giuliani Alexandre
Forest Laboratories Holdings Ltd.
Novexel Sa
Smart & Biggar
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