C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 239/94 (2006.01) A61K 31/517 (2006.01) A61K 51/04 (2006.01) A61P 17/06 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2375826
A radiolabeled compound of formula (I): is described R1 and R2 are each independently selected from the group consisting of hydrogen, alkyl, hydroxy, alkoxy, halo, haloalkyl, carboxy, carbalkoxy and salts thereof; and A, B, C and D are each independently selected from the group consisting of a hydrogen and an electon withdrawing group, provided that at least one of A, B, C and D is [18] fluorine.
Cette invention se rapporte à un composé radiomarqué, représenté par la formule (I), où R1 et R2 sont choisis chacun séparément dans le groupe constitué par hydrogène, alkyle, hydroxy, alcoxy, halo, haloalkyle, carboxy, carbalcoxy et des sels de ceux-ci; et A, B, C et D sont choisis chacun séparément dans le groupe constitué par un hydrogène et un groupe de prélèvement d'électrons, à condition qu'au moins l'un des éléments A, B, C et D représente [18] fluor.
Bonasera Thomas
Gazit Aviv
Levitzki Alexander
Mishani Eyal
Ortu Giuseppina
Hadasit Medical Research Services And Development Ltd.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Yissum Research Development Company Of The Hebrew University Of
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