Novel erythromycin derivatives, method for preparing same...

C - Chemistry – Metallurgy – 07 – H

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C07H 17/00 (2006.01) A61K 31/70 (2006.01) C07H 17/08 (2006.01)

Patent

CA 2261098

Compounds of formula (I), wherein R is hydrogen, alkyl optionally substituted by halogen or a (CH2)mAr radical or a radical (a), where m is an integer from 1 to 8, each of n and p, which are the same or different, is an integer from 0 to 6, each of A and B, which are the same or different, is hydrogen or halogen or alkyl, and Ar is aryl or heteroaryl, and Z is hydrogen or a carboxylic acid residue; a method for preparing same, and the use of said compounds as drugs, are disclosed.

Composés de formule (I) dans lesquels R est un hydrogène, un alkyle, éventuellement substitué par un halogène ou un radical (CH2)mAr ou un radical (a), dans lesquels m est un nombre entier (1 - 8), n et p identiques ou différents représentent un nombre entier (0 - 6), A et B identiques ou différents représentent un hydrogène ou un halogène ou un alkyle et Ar représente un aryle ou hétéroaryle, et Z représente un hydrogène ou le reste d'un acide carboxylique, procédé de préparation et application comme médicaments.

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