C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/18 (2006.01) A61K 38/00 (2006.01) A61K 38/18 (2006.01) C07K 14/50 (2006.01) C07K 16/22 (2006.01) C07K 19/00 (2006.01) C12N 5/10 (2006.01) C12P 21/02 (2006.01)
Patent
CA 2269083
The present invention relates to polynucleotide and polypeptide molecules for zFGF-5, a novel member of the FGF family. The polypeptides, and polynucleotides encoding them, are proliferative for muscle cells and may be used for remodelling cardiac tissue and improving cardiac function. The present invention also includes antibodies to the zFGF-5 polypeptides.
Cette invention a trait à un polynucléotide et à des molécules polypeptidiques pour zFGF-5, un nouveau membre de la famille des FGF. Les polypeptides et les polynucléotides les codant, qui font proliférer les cellules musculaires, peuvent être utilisés pour remodeler le tissu cardiaque et améliorer la fonction cardiaque. Cette invention concerne également des anticorps allant contre les polypeptides de zFGF-5.
Bukowski Thomas R.
Conklin Darrell C.
Deisher Theresa A.
Hansen Birgit
Holderman Susan D.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Zymogenetics Inc.
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