C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/14 (2006.01) A61K 31/444 (2006.01) A61K 31/506 (2006.01) A61P 35/00 (2006.01) C07D 403/14 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01) C07D 471/04 (2006.01) C07D 498/04 (2006.01)
Patent
CA 2718936
New substituted heterocyclic compounds, compositions containing them, and methods of using them for the inhibition of Raf kinase activity are provided. The new compounds and compositions may be used either alone or in combination with at least one additional agent for the treatment of a Raf kinase mediated disorder, such as cancer.
La présente invention concerne de nouveaux composés hétérocycliques substitués, des compositions les contenant et leurs procédés dutilisation dans le cadre de linhibition de lactivité de la Raf kinase. Les nouveaux composés et compositions peuvent être utilisés soit seuls, soit en combinaison avec au moins un agent supplémentaire afin de traiter un trouble induit par la Raf kinase, tel que le cancer.
Antonios-Mccrea William R.
Huang Zilin
Jin Jeff
Machajewski Timothy D.
Mckenna Maureen
Fetherstonhaugh & Co.
Novartis Ag
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