C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 409/04 (2006.01) C07D 215/42 (2006.01) C07D 215/48 (2006.01) C07D 215/50 (2006.01) C07D 401/06 (2006.01) C07D 401/10 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 405/04 (2006.01) C07D 409/12 (2006.01) C07D 409/14 (2006.01) C07D 413/12 (2006.01) C07D 417/04 (2006.01) C07D 417/06 (2006.01) C07D 417/10 (2006.01)
Patent
CA 2619706
Quinoline-based inhibitors of cyclin dependent kinase 2, compositions including the inhibitors, and methods of using the inhibitors and inhibitor compositions are described. The inhibitors and compositions including them are useful for treating disease or disease symptoms. The invention also provides for methods of making CDK-2 inhibitor compounds, methods of inhibiting CDK-2, and methods for treating disease or disease symptoms.
L'invention concerne des inhibiteurs de la kinase 2 dépendant des cyclines à base de quinoline, des compositions comprenant ces inhibiteurs et des procédés d'utilisation des inhibiteurs et des compositions d'inhibiteurs. Ces inhibiteurs et les compositions comprenant ceux-ci sont utiles pour traiter une maladie ou des symptômes pathologiques. L'invention concerne aussi des procédés de fabrication de composés d'inhibiteurs de la CDK-2, de procédés d'inhibition de la CDK-2 et des méthodes de traitement d'une maladie ou de symptômes pathologiques.
Curran Patrick J.
Deng Yongqi
Duca Jose S.
Fischmann Thierry O.
Hruza Alan W.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Schering Corporation
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