C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 19/23 (2006.01) A61K 31/7056 (2006.01) A61P 25/00 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2463923
The invention concerns a compound of formula (I), wherein: R¿1? and R¿2? represent each a group selected among hydrogen, alkyl, arylalkyl, hydroxy, hydroxylalkyl, dihydroxyalkyl, alkoxy, alkoxyalkyl, amino and aminoalkyl (optionally substituted); Ra and Rb represent each an alkylene chain; X¿1? and X¿2? represent each a group selected among hydroxy, alkoxy, aryloxy, arylalkoxy, alkyl, amino (optionally substituted), halogen, alkylcarbonyloxy and azido; X¿4? represent a methylidene group or a group of formula -Rc-X¿1? such as defined in their description; their isomers and their addition salts to a pharmaceutically acceptable acid or base. The invention is for use as medicines.
Composé de formule (I) dans laquelle: - R1 et R2 représentent chacun un groupement choisi parmi hydrogène, alkyle, arylalkyle, hydroxy, hydroxylalkyle, dihydroxyalkyle, alkoxy, alkoxyalkyle, amino et aminoalkyle (étant éventuellement substitués), - Ra et Rb représentent chacun une chaîne alkylène, - X1, X2 et X3 représentent chacun un groupement choisi parmi hydroxy, alkoxy, aryloxy, arylalkoxy, alkyle, amino (éventuellement substitué), halogène, alklcarbonyloxy et azido, - X4 représente un groupement méthylidène ou un groupement de formule -Rc-X1 tel que défini dans la description, leurs isomères ainsi que leurs sels d'addition à un acide ou à une base pharmaceutiquement acceptable. Médicaments.
Bizot-Espiard Jean-Guy
Hickman John
Marminon Christelle
Moreau Pascale
Pfeiffer Bruno
Les Laboratoires Servier
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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