A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/44 (2006.01) A61K 31/315 (2006.01) A61K 31/4439 (2006.01) A61K 31/555 (2006.01) C07D 487/04 (2006.01) C07F 3/00 (2006.01) C07F 3/06 (2006.01)
Patent
CA 2308135
Invented are metal chelated dimeric cell-surface receptor ligands, pharamceutical compositions containing these compounds, and methods of using these compounds as agonist of dimeric cell-surface receptors. Also invented are novel processes used in preparing these compounds. Also invented are novel receptor binding moieties of the invented metal chelated cell-surface receptor ligands.
L'invention concerne des ligands à chélation métallique de récepteurs de surface cellulaire dimères, des compositions pharmaceutiques contenant ces composés et des méthodes consistant à utiliser ces composés comme agonistes de récepteurs dimères de la surface cellulaire. L'invention concerne en outre de nouveaux procédés permettant de préparer ces composés, ainsi que de nouvelles fractions fixatrices présentes dans les ligands à chélation métallique de récepteurs de surface cellulaires décrits.
Gleason John G.
Luengo Juan I.
Miller Stephen G.
Gowling Lafleur Henderson Llp
Ligand Pharmaceuticals
Smithkline Beecham Corporation
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