C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/57 (2006.01) C07K 16/40 (2006.01) C12N 5/10 (2006.01) C12N 9/64 (2006.01) C12Q 1/37 (2006.01) C12Q 1/68 (2006.01) G01N 33/573 (2006.01)
Patent
CA 2325599
The invention concerns an isolated polypeptide comprising an amino acid sequence selected among the sequence SEQ ID n· 2 or n· 4, a sequence derived from or homologous with said sequence SEQ ID n· 2 or n· 4, or a biologically active fragment of said sequence SEQ ID n· 2 or n· 4, said isolated polypeptide being designated as "NEP II", and the use of said NEP II polypeptide for screening inhibitors useful in therapy.
Cette invention concerne un polypeptide isolé comprenant une séquence d'acides aminés choisie parmi la séquence SEQ ID n~ 2 ou n~ 4, une séquence dérivée ou homologue de ladite séquence SEQ ID n~ 2 ou n~ 4, ou un fragment biologiquement actif de ladite séquence SEQ ID n~ 2 ou n~ 4, ledit polypeptide isolé étant désigné par "NEP II", ainsi que l'utilisation dudit polypeptide NEP II pour le criblage d'inhibiteurs utiles en thérapie.
Bonhomme Marie-Chantal
Facchinetti Patricia
Gros Claude
Ouimet Tanja
Rose Christiane
Institut National de La Sante Et de La Recherche Medicale (inser
Robic
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