Novel nucleotide and amino acid sequences, and methods of...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/54 (2006.01) C07H 21/00 (2006.01) C07K 14/47 (2006.01) C07K 14/82 (2006.01) C07K 16/18 (2006.01) C12N 9/12 (2006.01) C12N 15/12 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/574 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2637267

The present invention relates to diagnostic markers comprising novel splice variants of known proteins and polynucleotides encoding same, useful in the qualitative and/or quantitative detection of various diseases and/or pathological conditions in a subject, and to the use of known proteins and polynucleotides encoding same for diagnosis. Particularly, the invention relates to the daignosis of a disease in a sample of body fluid or secretion obtained from the subject, and to the diagnosis of cancer.

La présente invention concerne des marqueurs de diagnostic comprenant de nouveaux variants d'épissage de protéines connues et des polynucléotides codant pour ceux-ci, utiles dans la détection qualitative et/ou quantitative de diverses maladies et/ou conditions pathologiques chez un sujet, et l'utilisation de protéines connues et de polynucléotides codant pour celles-ci pour le diagnostic. En particulier, l'invention concerne le diagnostic d'une maladie dans un échantillon de fluide corporel ou de sécrétion provenant du sujet, ainsi que le diagnostic du cancer.

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