Novel peptide nucleic acids

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) A61K 31/70 (2006.01) A61K 38/00 (2006.01) A61K 47/48 (2006.01) C07H 21/00 (2006.01) C07K 2/00 (2006.01) C07K 14/00 (2006.01) C12N 15/11 (2006.01)

Patent

CA 2161230

A novel class of compounds, known as peptide nucleic acids, bind complementary ssDNA and RNA strands more strongly than a corresponding DNA. The peptide nucleic acids generally comprise ligands such as naturally occurring DNA bases attached to a peptide backbone through a suitable linker.

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