Novel pharmaceutical compositions

Details Novel pharmaceutical compositions Novel pharmaceutical compositions

C - Chemistry, Metallurgy

07

D

C07D 235/06 (2006.01) A61K 31/4184 (2006.01) A61K 31/422 (2006.01) A61P 5/14 (2006.01) C07D 235/08 (2006.01) C07D 235/10 (2006.01) C07D 235/14 (2006.01) C07D 235/18 (2006.01) C07D 235/24 (2006.01) C07D 235/28 (2006.01) C07D 235/30 (2006.01) C07D 403/04 (2006.01) C07D 407/04 (2006.01) C07D 413/04 (2006.01)

Patent

CA 2649882

The invention provides the use of compounds of formula (I) or pharmaceutically acceptable esters, amides, solvates or salts thereof, including salts of such esters or amides, and solvates of such esters, amides or salts, for the manufacture of a medicament for the treatment or prophylaxis of a condition that may be treated with a thyroid receptor agonist or partial agonist wherein R1, R2, R3, R4, Y, W and R5 are as defined in the specification. The invention also provides compounds of formula (Ia) or pharmaceutically acceptable esters, amides, solvates or salts thereof, including salts of such esters or amides, and solvates of such esters, amides or salts, formula (Ia) wherein R1, R2, R3, R4, Y, W and R5 are as defined in the specification.

La présente invention concerne l'utilisation de composés de formule (I) ou leurs esters, leurs amides, leurs solvates ou leurs sels pharmaceutiquement acceptables, y compris les sels desdits esters ou amides et les solvates desdits esters, amides ou sels, pour la fabrication d'un médicament thérapeutique ou prophylactique d'une affection qui peut être traitée par un agoniste ou un agoniste partiel d'un récepteur thyroïdien. Dans ladite formule R1, R2, R3, R4, Y, W et R5 sont tels que définis dans le mémoire descriptif. L'invention concerne également des composés de formule (Ia) ou leurs esters, leurs amides, leurs solvates ou leurs sels pharmaceutiquement acceptables, y compris les sels desdits esters ou amides et les solvates desdits esters, amides ou sels, dans laquelle R1, R2, R3, R4, Y, W et R5 sont tels que définis dans le mémoire descriptif.

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