Novel physiologically active substance sulphostin, process...

Details Novel physiologically active substance sulphostin, process... Novel physiologically active substance sulphostin, process...

C - Chemistry, Metallurgy

12

N

C12N 1/20 (2006.01) C07G 99/00 (2009.01) A61K 35/74 (2006.01) C12N 9/99 (2006.01) C12P 1/06 (2006.01) C12N 9/64 (2006.01)

Patent

CA 2310400

This invention provides a physiologically active substance having a strong dipeptidyl peptidase IV inhibitory activity. The physiologically active substance sulphostin is obtained by culturing a microorganism belonging to the genus Streptomyces and having an ability to produce the physiologically active substance sulphostin, producing and accumulating this substance in the cultures, and harvesting it from the cultures.

L'invention concerne une substance physiologiquement active, la sulphostine, qui a un puissant effet inhibiteur de dipeptidylpeptidase IV. On obtient cette substance par mise en culture d'un micro-organisme qui appartient au genre Streptomyces et qui est capable de produire ladite substance de manière à permettre son accumulation et sa récolte dans le milieu de culture.

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