C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) A61K 31/70 (2006.01) A61K 39/04 (2006.01) A61K 48/00 (2006.01) C07K 7/08 (2006.01) C07K 14/35 (2006.01) C07K 16/12 (2006.01) C12N 1/21 (2006.01) C12N 1/36 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/569 (2006.01)
Patent
CA 2241023
The invention provides a nucleotide sequence representing a pathogenicity island found in species of pathogenic mycobacteria. The islands are shown as SEQ ID NOs: 3 and 4 and comprises several open reading frames encoding polypeptides. These polypeptides and their use in diagnosis and therapy form a further aspect of the invention.
L'invention concerne une séquence de nucléotides représentant un îlot à caractère pathogène que l'on trouve dans des espèces de mycobactéries pathogènes. Ces îlots sont représentés en tant que SEQ ID NOs: 3 et 4 et comprennent plusieurs cadres de lecture ouverts codant des polypeptides. Ces polypeptides et leur utilisation diagnostique et thérapeutique constituent un autre aspect de l'invention.
Doran Tim
Ford John
Hermon-Taylor John
Loughlin Mark
Millar Douglas
Mccarthy Tetrault Llp
St. George's Hospital Medical School
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