Novel proteins and nucleic acids encoding same

Details Novel proteins and nucleic acids encoding same Novel proteins and nucleic acids encoding same

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/00 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 3/10 (2006.01) A61P 9/00 (2006.01) A61P 9/10 (2006.01) A61P 35/00 (2006.01) A61P 43/00 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C07K 16/28 (2006.01) C07K 16/46 (2006.01) C12N 1/15 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/09 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/15 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) G01N 33/563 (20

Patent

CA 2416452

Disclosed herein are nucleic acid sequences that encode G-coupled protein- receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospeficically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human acids and proteins.

L'invention porte sur des séquences d'acides nucléiques qui codent des polypeptides du récepteur couplé à la nouvelle protéine G. L'invention porte également sur des polypeptides codés par ces séquences d'acides nucléiques et sur des anticorps qui de lient de manière immunospéficique au polypeptide, ainsi que des dérivés, des variants, des mutants ou des fragments du polypeptide, du polynucléotide ou de l'anticorps précité. Cette invention porte également sur des méthodes diagnostiques, thérapeutiques et de recherche pour diagnostiquer, traiter et prévenir des troubles dans lesquels intervient l'un quelconque des ces acides et protéines humains.

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