C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2497539
In its many embodiments, the present invention provides a novel class of pyrazolo~1,5-a~pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.
Dans ses multiples formes de réalisation, la présente invention se rapporte à une nouvelle classe de composés pyrazoloÝ1,5-a¨pyrimidine qui sont utiles en tant qu'inhibiteurs des kinases dépendantes des cyclines, des méthodes de préparation de ces composés, des compositions pharmaceutiques contenant un ou plusieurs de ces composés, des méthodes de préparation de formulations pharmaceutiques comprenant au moins un de ces composés et des méthodes de traitement, de prévention, d'inhibition ou d'amélioration d'au moins une maladie associée aux kinases dépendantes des cyclines au moyen de ces composés ou de ces compositions pharmaceutiques.
Dillard Lawrence W.
Doll Ronald J.
Dwyer Michael P.
Girijavallabhan Viyyoor Moopil
Guzi Timothy J.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Pharmacopeia Inc.
Pharmacopeia Drug Discovery Inc.
Schering Corporation
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