Novel pyridine compounds, process for their preparation and...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 213/74 (2006.01) A61K 31/44 (2006.01) A61K 31/4439 (2006.01) A61K 31/4545 (2006.01) A61K 31/496 (2006.01) A61K 31/5377 (2006.01) C07D 401/04 (2006.01) C07D 405/10 (2006.01)

Patent

CA 2581623

The present invention provides new heterocyclic compounds, particularly substituted pyridines, methods and compositions for making and using these heterocyclic compounds, and methods for treating a variety of diseases and disease states, including atherosclerosis, arthritis, restenosis, diabetic nephropathy, or dyslipidemia, or disease states mediated by the low expression of Perlecan.

La présente invention a trait à de nouveaux composés hétérocycliques, notamment des pyridines substituées, à des procédés et des compositions pour la fabrication et l'utilisation de ces composés hétérocycliques, et à des procédés pour le traitement d'une variété de maladies et d'états morbides, comprenant l'athérosclérose, l'arthrite, la resténose, la néphropathie diabétique, ou la dyslipidémie, ou d'états morbides médiés par une faible expression de perlecane.

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