Novel pyridone carboxylic acid derivatives

Details Novel pyridone carboxylic acid derivatives Novel pyridone carboxylic acid derivatives

C - Chemistry, Metallurgy

07

D

C07D 209/52 (2006.01) C07D 221/04 (2006.01)

Patent

CA 2226406

The present invention relates to a compound of the formula: (see fig. I) wherein is 1 or 2; R3 and R4 each represent a hydrogen atom or a lower alkyl group, with a proviso that, if n is 2, one of R3 and R4 is a hydrogen atom; R5 and R6 each represent a hydrogen atom, or a hydroxy, a lower alkoxy or an amino group which is unsubstituted or substituted by a lower alkyl group, with provisos that one of R5 and R6 is a hydrogen atom and that if n is 1 and one of R5 and R6 is an amino group, then at least one of R3 and R4 is other than hydrogen and that if n is 1, at least one of R3, R4, R5, and R6 is other than hydrogen. These compounds are useful as intermediates in preparing antibacterial compounds.

La présente invention concerne un composé de formule : (voir fig. I) où n est 1 ou 2; R3 et R4 représentent l'un et l'autre un atome d'hydrogène ou un groupe alkyle inférieur, à la condition que si n est 2, l'un parmi R3 et R4 est un atome d'hydrogène; R5 et R6 représentent l'un et l'autre un atome d'hydrogène ou un hydroxy, un alcoxy inférieur ou un amino qui est non substitué ou substitué par un groupe alkyle inférieur, à la condition que si un parmi R5 et R6 est un atome d'hydrogène et que si n est 1 et un parmi R5 et R6 est un groupe amino, alors au moins un parmi R3 et R4 n'est pas un atome d'hydrogène et que si n est 1, au moins un parmi R3, R4, R5 et R6 n'est pas un atome d'hydrogène. Ces composés sont utiles comme intermédiaires dans la préparation de composés antibactériens.

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