Novel pyrrolidine derivatives as inhibitors of coagulation...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 409/14 (2006.01) A61K 31/4439 (2006.01) A61P 7/00 (2006.01)

Patent

CA 2629080

The invention is concerned with novel pyrrolidine derivatives of formula (I) wherein X, Y, R1, R2 and R3 are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds inhibit the coagulation factor Xa and can be used as medicaments.

La présente invention concerne des dérivés innovants de la pyrrolidine de formule (I), dans laquelle X, Y, R1, R2 et R3 sont tels que définis dans la description et dans les revendications, de même que leurs sels physiologiquement acceptables. Ces composés inhibent le facteur de coagulation Xa et ils peuvent être utilisés en tant que médicaments.

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