C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/12 (2006.01) A61K 31/4709 (2006.01) A61P 9/02 (2006.01) C07D 401/14 (2006.01) C07D 471/04 (2006.01)
Patent
CA 2473892
The invention relates to novel 1-pyridin-4-yl urea derivatives of formulas 1 and 2 (see formula 1) (see formula 2) and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as neurohormonal antagonists.
L'invention concerne de nouveaux dérivés de 1-pyridin-4-yl urée, des composés apparentés et leur utilisation en tant qu'ingrédients actifs dans la préparation de compositions pharmaceutiques. Elle concerne également des aspects correspondants, tels que des procédés de préparation de ces composés, des compositions pharmaceutiques contenant un ou plusieurs de ces composés et particulièrement leur utilisation en tant qu'antagonistes neurohormonaux.
Aissaoui Hamed
Binkert Christoph
Clozel Martine
Mathys Boris
Mueller Claus
Actelion Pharmaceuticals Ltd
Gowling Lafleur Henderson Llp
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