C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 9/38 (2006.01) A61K 31/165 (2006.01) A61K 31/35 (2006.01) A61K 31/66 (2006.01) A61K 38/05 (2006.01) C07C 237/22 (2006.01) C07D 307/89 (2006.01) C07D 307/92 (2006.01) C07F 9/12 (2006.01) C07F 9/655 (2006.01) C07K 5/06 (2006.01) G01N 33/566 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2309792
This invention concerns compounds for inhibiting intracellular signal transduction, especially intracellular signal transduction mediated by one or more molecular interactions involving a phosphotyrosine-containing protein. This invention also relates to pharmaceutical compositions containing the compounds and prophylactic and therapeutic methods involving pharmaceutical and veterinary administration of the compounds. The compounds are of formula (I) as defined herein.
Cette invention concerne des composés destinés à inhiber la transduction de signal intracellulaire, notamment la transduction d'un signal intracellulaire médiée par une ou plusieurs interactions moléculaires impliquant une protéine contenant de la phosphotyrosine. Cette invention concerne également des compositions pharmaceutiques contenant les composés ainsi que des méthodes prophylactiques et thérapeutiques faisant intervenir l'administration pharmaceutique et vétérinaire des composés. Les composés ont la formule (I) telle que ci-définie.
Bohacek Regine
Jacobsen Virginia A.
Kawahata Noriyuki H.
Luke George P.
Macek Karina
Ariad Pharmaceuticals Inc.
Borden Ladner Gervais Llp
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