Novel substituted 2,3-benzodiazepine derivatives

Details Novel substituted 2,3-benzodiazepine derivatives Novel substituted 2,3-benzodiazepine derivatives

C - Chemistry, Metallurgy

07

D

C07D 243/10 (2006.01) A61K 31/55 (2006.01) C07D 243/02 (2006.01) C07D 417/04 (2006.01) C07D 487/02 (2006.01) C07D 491/00 (2006.01) C07D 491/04 (2006.01)

Patent

CA 2512616

The invention relates to new 2,3-benzodiazepine derivatives of formula (I), isomers and acid addition salts thereof and to pharmaceutical compositions containing the same, as well as to pharmaceutical compositions and methods of using the same suitable for treating conditions associated with muscle spasms, epilepsy, acute and chronic forms of neurodegenerative diseases as well as preventing, treating or alleviating the symptoms of acute and chronic inflammatory disorders.

L'invention concerne de nouveaux dérivés de 2,3-benzodiazépines, représentés par la formule (I), des isomères et des sels d'addition d'acides de ces dérivés et des compositions pharmaceutiques contenant ces composés, ainsi que des compositions pharmaceutiques et des méthodes d'utilisation desdits composés pour traiter des états associés à des spasmes musculaires, l'épilepsie, des formes aiguës et chroniques de maladies neurodégénératives, de même que pour prévenir, traiter ou atténuer les symptômes de troubles inflammatoires aigus et chroniques.

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