Novel succinate derivative compounds useful as cysteine...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 413/12 (2006.01) A61K 31/5375 (2006.01) A61K 31/5377 (2006.01) A61P 9/10 (2006.01) A61P 25/28 (2006.01) A61P 37/00 (2006.01) C07D 295/18 (2006.01) C07D 295/185 (2006.01)

Patent

CA 2379747

Disclosed are novel succinate derivative compounds of formula (I)/(Ia): wherein R1, R2, R3, R4, R5, R6, R7, X and A are defined herein. The compounds are useful as inhibitors of cysteine proteases. Also disclosed are methods of using and methods of making such compounds.

L'invention concerne de nouveaux composés de dérivés de succinate représentés par la formule (I)/(Ia), R1, R2, R3, R4, R5, R6, R7, X et A étant définis dans le descriptif. Ces composés sont utilisés comme inhibiteurs des cystéine protéases. L'invention concerne également des procédés d'utilisation, et des procédés de préparation de ces composés.

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