Novel sulfamate compounds for medical use

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 307/02 (2006.01) A61K 31/095 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2700568

This invention relates to sulfamates of Formula (I), wherein R1 to R3 and n are defined in the claims, having carbonic anhydrase enzyme inhibitory activity, to medicaments comprising these compounds, to pharmaceutical compositions comprising these compounds, and to processes for the preparation of these compounds. The invention is also directed to the use of such compounds, medicaments and compositions, particularly to their use in administering them to patients to achieve a therapeutic effect.

La présente invention concerne des sulfamates de formule (I), les R1 à R3 et n étant tels que définis dans les revendications. Ces sulfamates présentent une activité inhibitrice de l'enzyme anhydrase carbonique. L'invention concerne également des médicaments comprenant ces composés, des compositions pharmaceutiques comprenant ces composés, et des procédés de préparation de ces composés. L'invention concerne en outre l'utilisation de tels composés, médicaments et compositions, en particulier leur utilisation pour administration à des patients afin d'obtenir un effet thérapeutique.

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