Novel tricyclic azepine derivatives, method for production...

C - Chemistry – Metallurgy – 07 – D

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C07D 513/04 (2006.01) A61K 31/55 (2006.01) C07D 515/04 (2006.01)

Patent

CA 2513059

The invention relates to compounds of formula (I), where (a) is a benzyl or pyridyl group, optionally fused at position ( 2-3, 3-4, or 4-5), and optionally substituted, (W) is a X-Y or Y-X group, where (X) is a group (b) and (Y) is an oxygen atom or a (N-R¿3?) group, n is zero or a whole number where 1 = n = 6 and G, R¿1?, R¿2 ?and R¿3? are as defined in the description, the enantiomers, diastereomers and the addition salts thereof with a pharmaceutically-acceptable acid or base. The invention relates to medicaments.

Composé de formule (I) : dans laquelle (a) représente un groupement benzo ou pyrido, éventuellement fusionné en position ( 2-3, 3-4, ou 4-5), et éventuellement substitué, (W) représente un groupement ( X-Y ou Y-X) avec (X) représentant un groupement (b), et Y représentant un atome d'oxygène ou un groupement (N-R3), n représente zéro ou un entier tel que (1 <= n <= 6 (G, R1, R2et R3) sont tels que définis dans la description, leurs énantiomères, diastéréoisomères, ainsi que leurs sels d'addition à un acide ou à une base pharmaceutiquement acceptable. Médicaments.

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