Novel vitamin d3 analogues

C - Chemistry – Metallurgy – 07 – F

Patent

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Details

C07F 7/18 (2006.01) C07C 401/00 (2006.01)

Patent

CA 2076772

The invention relates to vitamin D3 analogues of the formula: (see formula I) wherein R1 is a hydrogen atom and R2 is hydroxy, or R1 is hydroxy and R2 is a hydro<3en atom, X is a hydrogen atom, hydroxy or a hydroxy protected by a hydroxy-protecting group, and R3 is a hydrogen atom or a hydroxy-protecting group. These compounds have vitamin D3-like activities such as the ability to control calcium metabolism and the ability to induce tumor cell differentiation.

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