Nuclear receptor binding agents

Details Nuclear receptor binding agents Nuclear receptor binding agents

C - Chemistry, Metallurgy

07

C

C07C 233/65 (2006.01) A61K 31/165 (2006.01)

Patent

CA 2631331

The present invention relates to a novel class of selective estrogen receptor modulators (SERMs). The SERM compounds are applicable for use in the prevention and/or treatment of a variety of diseases and conditions including prevention and treatment of cancers such as prostate and breast cancer, osteoporosis, hormone-related diseases, hot flashes or vasomotor symptoms, neurological disorders, cardiovascular disease and obesity.

L'invention concerne une nouvelle catégorie de modulateurs sélectifs des récepteurs oestrogéniques (SERM). Ces composés SERM peuvent servir dans la prévention et/ou le traitement d'une pluralité de maladies et d'états, y compris pour prévenir et traiter des cancers tels que le cancer de la prostate et du sein, l'ostéoporose, des maladies hormonales, des bouffées de chaleur ou des symptômes vasomoteurs, des troubles neurologiques, des maladies cardio-vasculaires et l'obésité.

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