Nucleic acid biosensor diagnostics

C - Chemistry – Metallurgy – 12 – Q

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Details

C12Q 1/68 (2006.01) G01N 21/77 (2006.01)

Patent

CA 2208165

A biosensor for detecting a target nucleic acid, which has at least three layers, two of which are a waveguide, wherein one layer includes a nucleic acid or nucleic acid analog capable of hybridizing to the target nucleic acid, and wherein a flurophore is tethered to the nucleic acid or nucleic acid analog and wherein the biosensor functions according to direct excitation.

Biodétecteur pour déceler un acide nucléique cible, possédant au moins trois couches, dont deux sont un guide d'ondes; l'une des couches renferme un acide nucléique ou un analogue d'acide nucléique pouvant hybrider l'acide nucléique cible; un fluorophore est lié à l'acide nucléique ou à l'analogue d'acide nucléique, et le biodétecteur fonctionne en mode d'excitation directe.

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