Nucleic acids and polypeptides having altered expression in...

Details Nucleic acids and polypeptides having altered expression in... Nucleic acids and polypeptides having altered expression in...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61P 1/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2351167

The invention is directed to purified and isolated polypeptides, the nucleic acids encoding such polypeptides that have altered expression characteristics in the T84 gut barrier model, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, fragmented peptides derived from these polypeptides, and the uses to study inflammatory bowel diseas (IBD).

L'invention porte sur de nouveaux polypeptides purifiés et isolés, sur des acides nucléiques codant ces polypeptides, sur des procédés de production de formes de recombinaison de ces polypeptides, sur des anticorps générés contre ces polypeptides, sur des fragments peptidiques dérivés de ces polypeptides et sur les utilisations de ces polypeptides.

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