C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 38/00 (2006.01) C07H 21/04 (2006.01) C07K 1/00 (2006.01) C12N 1/20 (2006.01) C12N 15/00 (2006.01) C12P 21/06 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2393941
The present invention relates to novel proteins. More specifically, isolated nucleic acid molecules are provided encoding novel polypeptides. Novel polypeptides and antibodies that bind to these polypeptides are provided. Also provided are vectors, host cells, and recombinant and synthetic methods for producing human polynucleotides and/or polypeptides, and antibodies. The invention further relates to diagnostic and therapeutic methods useful for diagnosing, treating, preventing and/or prognosing disorders related to these novel polypeptides. The invention further relates to screening methods for identifiying agonists and antagonists of polynucleotides and polypeptides of the invention. The present invention further relates to methods and/or compositions for inhibiting or enhancing the production and function of the polypeptides of the present invention.
La présente invention concerne de nouvelles protéines. Plus spécifiquement, l'invention concerne des molécules d'acide nucléique isolées, codant pour de nouveaux polypeptides. Cette invention concerne également : de nouveaux polypeptides et anticorps qui se lient à ces polypeptides ; des vecteurs, des cellules hôtes, et des procédés de recombinaison et de synthèse permettant de produire des polynucléotides et/ou polypeptides humains, et des anticorps ; des procédés diagnostiques et thérapeutiques utiles pour le diagnostic, le traitement, la prévention et/ou la prévision de troubles liés à ces nouveaux polypeptides ; des procédés de criblage permettant d'identifier des agonistes et des antagonistes de polynucléotides et polypeptides de l'invention ; des procédés et/ou des compositions permettant d'inhiber ou d'augmenter la production et la fonctionnalité des polypeptides de la présente invention.
Barash Steven C.
Birse Charles E.
Rosen Craig A.
Ruben Steven M.
Barash Steven C.
Birse Charles E.
Human Genome Sciences Inc.
Mbm & Co.
Rosen Craig A.
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