G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/574 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2509902
Disclosed are methods for detecting neoplastic or damaged cells and for detecting multidrug resistance in neoplastic or damaged cells by detecting an increase in the cell surface expression of a nucleophosmin (NPM) protein on the surface of such a multidrug resistant neoplastic or damaged cells as compared to the level of expression of the nucleophosmin protein on the surface of a normal cell.
La présente invention a trait à des procédés de détection de cellules néoplasiques ou endommagées et de détection de la multirésistance aux médicaments dans des cellules néoplasiques ou endommagées par la détermination d'une croissance dans l'expression en surface cellulaire d'une protéine nucléophosmine (NPM) à la surface de telles cellules néoplasiques ou endommagées à multirésistance aux médicaments par rapport à l'expression de la protéine nucléophosmine à la surface d'une cellule normale.
Bonneau Anne-Marie
Dallaire Frederic
Georges Elias
Serfass Lucile
Aurelium Biopharma Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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