C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) A61K 39/095 (2006.01) C07K 14/22 (2006.01) C07K 16/12 (2006.01) C07K 16/40 (2006.01) C12N 1/21 (2006.01) C12N 9/02 (2006.01) C12N 9/10 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2050749
The present invention is concerned with a method for the isolation of a nucleotide sequence which codes for a protein having a molecular weight of about 64 000 daltons, which is located on the outer membrane of N. meningitidis, as well as with the recombinant DNA obtained therefrom, which is used for the transformation of a host microorganism. The technical object pursued with the invention is the identification of a nucleotide sequence coding for a highly conserved and common protein for the majority of pathogenic Neisseria strains, the production of this protein with a high level of purity and in commercially useful amounts using the recombinant way, so that it can be used in diagnostic methods and vaccine preparations with a broad immunoprotection spectrum.
Acosta Anabel A.
Blanco Sonia G.
Cordova Vivian M.
Del Valle Rosales Jesus A.
Grillo Juan M.
Acosta Anabel A.
Blanco Sonia G.
Borden Ladner Gervais Llp
Centro de Ingenieria Genetica Y. Biotecnologia
Cordova Vivian M.
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