Nucleozymes

Details Nucleozymes Nucleozymes

C - Chemistry, Metallurgy

07

H

C07H 21/00 (2006.01) A61K 31/70 (2006.01) C12N 9/00 (2006.01) C12N 15/11 (2006.01) C12P 19/34 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2129119

2129119 9315187 PCTABScor01 Nucleozymes containing ribonucleotides and deoxyribonucleotides or nucleic acid analogues are described herein. The nucleozymes have catalytic activity and are significantly more resistant to degradation than their all-RNA ribozyme connterparts. Also described are methods for preparing the nucleozymes along with methods of using nucleozymes, e.g., as therapeutic agents.

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