O-acetyltransferase from neisseria meningitidis,...

Details O-acetyltransferase from neisseria meningitidis,... O-acetyltransferase from neisseria meningitidis,...

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) A61K 39/095 (2006.01) C12N 1/21 (2006.01) C12N 9/10 (2006.01) C12N 15/63 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2586710

Provided are recombinant DNA molecules that do not occur in nature encoding a Lot3 O-acetyltransferase, vectors that direct expression of a Lot O- acetyltransferase, recombinant host cells which express a Lot3 O- acetyltransferase, methods for recombinant production of a Lot3 O-acetyltransferase, methods for acetylating lipooligosaccharides, especially those of a Neisseria meningitidis using a recombinant Lot O-acetyltransferase, and immunogenic compositions comprising the acetylated Iipooligosaccharide.

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