Oligosaccharide-protein conjugates

Details Oligosaccharide-protein conjugates Oligosaccharide-protein conjugates

A - Human Necessities

61

K

A61K 47/48 (2006.01) A61P 3/00 (2006.01)

Patent

CA 2747230

Provided herein are conjugates comprising a protein and an oligosaccharide of one of Formulae I-VI. Also provided herein are pharmaceutical compositions comprising such conjugates. Further provided herein are methods of treating a lysosomal storage disorder in a mammal by administration of an oligosaccharide- glycoprotein conjugate.

Cette invention concerne des conjugués comprenant une protéine et un oligosaccharide répondant à l'une des Formules I-VI. L'invention décrit également des compositions pharmaceutiques comprenant ces conjugués. L'invention concerne, en outre, des méthodes de traitement d'une maladie lysosomale chez un mammifère par administration d'un conjugué oligosaccharide-glycoprotéine selon l'invention.

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