Oncofetal fibronectin as a marker for disease and other...

G - Physics – 01 – N

Patent

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G01N 33/574 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) C07K 16/18 (2006.01) C07K 16/32 (2006.01) C12Q 1/68 (2006.01) G01N 33/483 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) G01N 33/543 (2006.01) C07K 14/78 (2006.01)

Patent

CA 2575675

Methods and products for the detection of oncofetal fibronectin indicating molecules in samples are provided. Methods for imaging of oncofetal fibronectin are provided. In some methods provided herein, the sample is treated with a reagent and/or contacted with anon-specific binder. Provided are methods for testing subjects to ascertain health and disease status and to assess the risk of developing a disease or condition. Methods for detecting the presence of oncofetal fibronectin indicating molecules by a variety of methods such as immunoassays and mass spectrometry also are provided. Methods and products for detection of oncofetal fibronectin for selection of concepti are provided.

La présente invention a trait à des procédés et des produits pour la détection de molécules indicatives de la fibronectine oncofoetale dans des échantillons. L'invention a également trait à des procédés pour l'imagerie de la fibronectine oncofoetale. Dans certains procédés de l'invention, l'échantillon est traité avec un réactif et/ou mis en contact avec une liaison non spécifique. L'invention a trait en outre à des procédés pour tester des sujets en vue de constater le statut de santé et de maladie et d'évaluer le risque de développer une maladie ou une condition. L'invention a également trait à des procédés pour la détection de molécules indicatives de la fibronectine oncofoetale par divers procédés tels que des dosages immunologiques et la spectrométrie de masse. L'invention a trait enfin à des procédés pour la détection de la fibronectine oncofoetale pour la sélection de produits de conception.

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