Ophthalmic devices and related methods and compositions

A - Human Necessities – 61 – L

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A61L 27/24 (2006.01) A61F 2/14 (2006.01) A61L 27/54 (2006.01) G02B 1/00 (2006.01)

Patent

CA 2576308

Devices, methods, and compositions for improving vision or treating diseases, disorders or injury of the eye are described. Ophthalmic devices, such as corneal onlays, corneal inlays, and full-thickness corneal implants, are made of a material that is effective in facilitating nerve growth through or over the device. The material may include an amount of collagen greater than 1% (w/w), such as between about 10% (w/w) and about 30% (w/w). The material may include collagen polymers and/or a second biopolymer or water-soluble synthetic polymer cross-linked using EDC/NHS chemistry. The material may additionally comprise a synthetic polymer. The devices are placed into an eye to correct or improve the vision of an individual or to treat a disease, disorder or injury of an eye of an individual.

L~invention porte sur des dispositifs, des procédés et des compositions pour améliorer la vision ou traiter les maladies, les troubles ou les blessures de l~oeil. Les dispositifs ophtalmiques, comme les implants externes de la cornée, les implants internes de la cornée et les implants de cornée sur toute l~épaisseur, sont réalisés dans un matériau facilitant la croissance nerveuse à travers ou sur le dispositif. Le matériau peut englober une quantité de collagène supérieure à 1% (en poids), par exemple entre environ 10% (en poids) et environ 30% (en poids). Le matériau peut inclure des polymères collagènes et/ou un second biopolymère ou polymère synthétique soluble dans l~eau réticulé à l~aide de la chimie EDC/NHS. Le matériau peut en outre comprendre un polymère synthétique. Les dispositifs sont placés dans l~AEil pour corriger ou améliorer la vision d~un individu ou traiter une maladie, un trouble ou une blessure de l~AEil d~un individu.

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