Optically active thiazetoquinoline-3-carboxylic acid...

Details Optically active thiazetoquinoline-3-carboxylic acid... Optically active thiazetoquinoline-3-carboxylic acid...

C - Chemistry, Metallurgy

07

D

167/180, 167/227

C07D 513/04 (2006.01) A61K 31/47 (2006.01)

Patent

CA 2027778

ABSTRACT: An optically active thiazetoquinoline-3-carboxylic acid compound represented by the following formula (I): (I) Image wherein R1 is a hydrogen atom or a lower alkyl group; R2 is a fluorine atom or a chlorine atom; R3 is a hydrogen atom, a lower alkanoyl group, a halogenated lower alkanoyl, or the residue of carboxylic acid ester; and C * represents an asymmetric carbon atom of S- or R- configuration, a pharmacologically acceptable salt thereof, and a method for preparing the compound are disclosed. ALSO disclosed are antibacterial agent, antineoplastic agent, and anti-AIDS virus agent comprising the same, a pharmaceutical composition for the treatment of bacterial infectious disease, tumor, and AIDS comprising an effective amount of the same. - 68 -

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