Oral compositions of fenretinide having increased...

A - Human Necessities – 61 – K

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Details

A61K 31/167 (2006.01) A23L 1/30 (2006.01) A61K 9/00 (2006.01) A61K 9/14 (2006.01) A61K 47/10 (2006.01) A61K 47/14 (2006.01) A61K 47/24 (2006.01) A61K 47/26 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2513260

The present invention provides an edible composition for oral delivery of an active agent such as a retinide. The composition comprises, in the form of a dry flowable powder: (a) an active agent such as a retinide; (b) lipid matrix composition; (c) optionally sweetener; (d) flour. Compositions of the invention may be administered per se or mixed with a solid or liquid food carrier, for direct oral consumption by a subject or administration through a feeding tube.

L'invention concerne une composition comestible permettant de distribuer oralement un agent actif tel qu'un rétinide. Ladite composition comprend, sous forme de poudre fluide sèche: a) un agent actif tel qu'un rétinide; b) une composition matricielle lipidique; c) un édulcorant facultatif; d) de la farine. Les compositions de l'invention peuvent être administrées per se ou mélangées à un support alimentaire solide ou liquide, afin d'être consommées directement oralement par un sujet ou administrées par l'intermédiaire d'un tube d'alimentation.

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