Oral pharmaceutical composition

Details Oral pharmaceutical composition Oral pharmaceutical composition

A - Human Necessities

61

K

A61K 47/26 (2006.01) A61K 9/00 (2006.01) A61K 9/10 (2006.01) A61K 9/16 (2006.01) A61K 31/431 (2006.01) C07D 499/00 (2006.01) C07D 499/88 (2006.01)

Patent

CA 2354558

Attempts are made to develop a widely applicable technique for developing granules for oral use which can be quickly disintegrated or dissolved in the oral cavity at the administration or in the dissolution or suspension step in using and can be easily handled. Granules for oral use which are obtained by the granulation with the use of sucrose, contain no or little binders and quickly undergo disintegration or dissolution.

Des tentatives ont été faites pour mettre au point une technique largement applicable destinée à la fabrication de granulés pour administration orale qui peuvent se désintégrer ou se dissoudre rapidement dans la cavité buccale lors de l'administration ou lors de la phase de dissolution ou de suspension en cas de préparation préalable, et qui sont faciles à manier. Les granulés pour administration orale obtenus par granulation à l'aide de saccharose ne contiennent que peu de liants, voire aucun, et sont rapidement soumis à la désintégration ou à la dissolution.

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