Osteoimplant and method for making same

Details Osteoimplant and method for making same Osteoimplant and method for making same

A - Human Necessities

61

L

A61L 27/36 (2006.01)

Patent

CA 2409479

A method of manufacturing an osteoinductive osteoimplant is provided which comprises the steps of: demineralizing part or all of at least one surface of a monolithic section of cortical bone to a depth of at least about 100 microns; and, configuring the monolithic section of cortical bone to provide an osteoimplant possessing an outer surface possessing at least one demineralized zone and a non-demineralized zone. An implant produced according to the above method demonstrates improved osteoinduction without producing any clinically significant reduction of strength in critical regions of the osteoimplant.

L'invention concerne un procédé de fabrication d'un implant osseux ostéoinducteur, consistant à déminéraliser une partie ou l'ensemble d'au moins une surface d'une section monolithique de corticale jusqu'à une profondeur d'au moins 100 microns environ, et à configurer la section monolithique de corticale afin de réaliser un implant osseux présentant une surface extérieure comportant au moins une zone déminéralisée et une zone non déminéralisée. Un implant fabriqué selon ledit procédé offre une ostéoinduction améliorée sans créer de diminution de résistance ayant une importance clinique dans des zones critiques de l'implant osseux.

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