P-oxybenzoic acid derivatives, processes for their...

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C - Chemistry, Metallurgy

07

C

260/512.2, 260/5

C07C 65/21 (2006.01) A61K 31/19 (2006.01) C07C 65/24 (2006.01) C07C 65/40 (2006.01) C07D 303/04 (2006.01)

Patent

CA 1214784

- 28 - ABSTRACT OF THE DISCLOSURE P-oxybenzoic acid derivatives of formula (1) Image (1) wherein R1 is hydrogen, or straight or branched alkyl of one to four carbon atoms; n is 1 or 2; X is Image or Image ; and R2 is -OH or -NHCH2COOH; and non-toxic pharmaceuti- cally acceptable salts thereof, exhibit a hypo- lipemic effect. The compounds are prepared from the corresponding ester or acid halide compounds, wherein optionally the second- ary alcohol group may be oxidized to a keto group.

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